by Oligonucleotides are short single-stranded DNA or RNA polymers that are commonly used as probes for genetic research and diagnostics. They find application in gene expression studies, genomic analysis, antisense therapy development and molecular diagnostics due to their high binding affinity and specificity.
The global oligonucleotide synthesis market is estimated to be valued at US$ 3,962.67 Mn in 2023 and is expected to exhibit a CAGR of 11% over the forecast period 2023 to 2030, as highlighted in a new report published by Coherent Market Insights.
Market key trends:
Gene expression studies use oligonucleotides to investigate changes in gene expression patterns in response to external stimuli and hence provide valuable insights into normal and disease biological processes. They help in understanding complex phenotypes and identifying potential drug targets or disease biomarkers. Propelled by rising gene expression analyses worldwide, the oligonucleotide synthesis market is expected to witness significant growth over the forecast period. Better availability of RNA-seq technologies and growing interest in personalized medicine will further drive the demand for oligonucleotides in clinical diagnostics and research.
SWOT Analysis
Strength: The oligonucleotide synthesis market is driven by increasing R&D activities in pharmaceutical and biotechnology industries for disease diagnostics and therapeutics. Growing applications of oligonucleotides in diagnostic technologies and DNA sequencing is also boosting the market growth.
Weakness: High capital investment for oligonucleotide synthesis process and equipment. Maintaining quality standards and reducing production cost remain major challenges for players.
Opportunity: Growing healthcare expenditure in emerging nations presents lucrative growth opportunities. Advancements in technologies like digital PCR and next-generation sequencing are expanding applications of synthesized oligos.
Threats: Stringent regulatory environment increases compliance burden. Shift toward personalized medicine increases demand for custom-made oligos challenging mass production capabilities.
Key Takeaways
The Global Oligonucleotide Synthesis Market Size is expected to witness high growth at a CAGR of 11% during the forecast period of 2023 to 2030. The market size is projected to reach US$ 3962.67 Mn by 2023 from US$ 2090 Mn in 2018.
Regional analysis: North America currently dominates the global market due to extensive R&D spending and presence of key market players. Asia Pacific shows fastest growth owing to increasing healthcare spending, growing biopharma industry, and favorable government support for research. Countries like China, India and South Korea are emerging hubs for clinical trials and biologics production.
Key players: Key players operating in the oligonucleotide synthesis market are Thermo Fisher Scientific, Sigma-Aldrich Corporation, GE Healthcare, Integrated DNA Technologies, Inc., TriLink Biotechnologies€TM, Inc, BioAutomation Corporation, Twist Bioscience, Shanghai SynTheAll Pharmaceutical Co., CUSABIO Technology LLC, Synbio Technologies, GENEWIZ, Eurofins Scientific, Agilent Technologies, Kaneka Eurogentec S.A., and LGC, Biosearch Technologies. Thermo Fisher Scientific is the dominant player with wide geographical presence and product portfolio. Small players focus on specialized services and customized oligo synthesis.
Note:
1. Source: Coherent Market Insights, Public sources, Desk research
2. We have leveraged AI tools to mine information and compile it
